Eiturefnafræði lífrænna fosfórs

Eiturhrif hverrar tegundar geta verið mismunandi, flestar eru mjög eitraðar og mjög eitraðar og nokkrar eru með litla eiturhrif.

Sumar tegundir hafa eitrunaráhrif þegar þær eru notaðar í samsetningu, svo sem blöndur af malathion og trichlorfon, trichlorfon og asinphos.

Sumum afbrigðum er hægt að breyta til að auka eiturhrif. Til dæmis eykst eituráhrif 1605 eftir oxun og tríklórfoni er breytt í díklórvos í basískri lausn, sem er eitraðari.

Organophosphorus pesticides (organophosphate pesticides) form phosphorylated cholinesterase with cholinesterase in the body. The activity of cholinesterase is inhibited, so that the enzyme cannot decompose acetylcholine, resulting in excessive accumulation of acetylcholine in tissues. Overexcites cholinergic nerves, causing muscarinic, nicotinic, and central nervous system symptoms. Phosphorylated cholinesterase generally "ages" after about 48 hours and is not easy to recover.

Some ester hydrocarbyl and aromatic hydrocarbyl phosphate compounds still have delayed neurotoxicity, which is caused by organophosphorus pesticides inhibiting neuropathy target esterase (neurotoxic esterase) in vivo and causing it to "age", causing delayed neurotoxicity. Neuropathy. This toxic effect has nothing to do with cholinesterase activity.

Lífræn fosfór skordýraeitur í formi örhylkja með viðvarandi-losun hafa lengri verkunartíma.